Before installing the scanner software, make sure all anti-virus software is disabled.
If you had a non-Epson scanner previously installed on your computer, this may cause device conflicts with your Epson scanner. We recommend that you delete all scanner software (driver, scanning program, etc.) related to your previous scanner.
You may also have problems if you’re using a Macintosh with OS X 10.2.x or later and Classic is running in the background. We now have an updated driver which supports scanning in OS X while Classic is running. You can download the latest TWAIN Driver and Epson Scan Utility from the Perfection 2480 Photo Downloads page.