Epson Stylus Photo RX620, FAQ - Technical Support

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What should I do if I see the message Scanner Not Ready?

Do the following:

Make sure your RX620 is turned on and securely connected to your computer or USB hub.
If your RX620 is connected to a USB hub, make sure it’s connected to a first tier hub. The first tier hub is the hub closest to the host computer when more than one hub is connected to the computer.
Check to make sure the RX620’s transportation lock is unlocked.
Try restarting your computer.